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Furthermore, numerous signal transduction proteins (such as receptors and cytokines) also regulate the transcriptional landscape through the epigenome, resulting in the ultimate regulation of the immune response
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Enhanced responses of Th17 cells (IL-17, IL-23) and decreased responses of Treg cells (TGF-β, IL-10) and high ratios of Th17/Treg cells in SARS-CoV-2-infected patients has a strong relationship with hyperinflammation, eosinophilic responses, allergic disorders, lung damage, and COVID-19 disease pathogenesis (293)
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